Welcome to Zhengqing Ouyang's lab homepage. Our lab is part of The Jackson Laboratory for Genomic Medicine, University of Connecticut Institute for Systems Genomics, Department of Genetics and Genome Sciences, and Department of Biomedical Engineering. We are located on the campus of University of Connecticut Health Center.
The Ouyang Lab is focused on the development and application of
statistical and computational methodologies in the area of regulatory
genomics. We design and develop methods and tools for
high-dimensional multilevel data from next generation sequencing. We
dissect the structure, function and variation of the genome, epigenome,
transcriptome and epitranscriptome, and the dynamics of gene regulatory
networks. We build systems models for the genetic and
epigenetic mechanisms of complex phenotypes. Our research has broad
impact on precision genomic medicine for human health and diseases such
as development, aging, neurological diseases, and cancer.
11/2014 - Our lab has been affiliated with the Institute for Systems Genomics at University of Connecticut!
10/2014 - We are moving to our gorgeous new building!
01/2014 - Dr. Ouyang is featured in The Jackson Laboratory news GenomeWeb lists three JAX faculty among most promising young investigators!
01/2014 - Our collaborative paper about landscape and variation of RNA secondary structure across the human transcriptome has been published in Nature!
12/2013 - Dr. Ouyang has been awarded the Genome Technology Young Investigators of the Year Award!
10/2013 - Our collaborative paper about STAT3 targets on aggressive tumorigenesis in diffuse large B cell lymphoma has been published in G3: Genes, Genomes, Genetics!04/2013 - Our collaborative paper about RNA structure mapping using nuclease digestion and high-throughput sequencing has been published in Nature Protocols!
03/2013 - Our lab has been affiliated with the Department of Genetics and Genome Sciences at the University of Connecticut School of Medicine!
01/2013 - Our methodology paper about genome-scale RNA secondary structure reconstruction has been published in Genome Research!
01/2013 - Our lab has been affiliated with the Department of Biomedical Engineering at the University of Connecticut School of Engineering!
12/2012 - Dr. Ouyang is featured in The Jackson Laboratory news JAX Genomic Medicine appoints computational biologist to faculty!