Welcome to Zhengqing Ouyang's lab homepage. Our lab is part of The Jackson Laboratory for Genomic Medicine, University of Connecticut Institute for Systems Genomics, Department of Genetics and Genome Sciences, and Department of Biomedical Engineering. We are located on the campus of University of Connecticut Health Center.
The Ouyang Lab is focused on the development and application of
statistical and computational methodologies in genomics. We design and
develop methods and tools for big data from next generation sequencing
and other modern technologies at all cellular levels, including but are
not limited to genome, epigenome, transcriptome and epitranscriptome.
We dissect the structure, function, variation, and regulation of
chromatin and RNA, and the dynamics of molecular networks. We build
systems models for elucidating the genetic and epigenetic mechanisms of
complex phenotypes. Our research provides infrastructure of genomic data science
for precision medicine of human health and diseases, including
development, aging, neurological diseases, and cancer.
11/2014 - Our lab has been affiliated with the Institute for Systems Genomics at University of Connecticut!
10/2014 - We are moving to our gorgeous new building!
01/2014 - Dr. Ouyang is featured in The Jackson Laboratory news GenomeWeb lists three JAX faculty among most promising young investigators!
01/2014 - Our collaborative paper about landscape and variation of RNA secondary structure across the human transcriptome has been published in Nature!
12/2013 - Dr. Ouyang has been awarded the Genome Technology Young Investigators of the Year Award!
10/2013 - Our collaborative paper about STAT3 targets on aggressive tumorigenesis in diffuse large B cell lymphoma has been published in G3: Genes, Genomes, Genetics!04/2013 - Our collaborative paper about RNA structure mapping using nuclease digestion and high-throughput sequencing has been published in Nature Protocols!
03/2013 - Our lab has been affiliated with the Department of Genetics and Genome Sciences at the University of Connecticut School of Medicine!
01/2013 - Our methodology paper about genome-scale RNA secondary structure reconstruction has been published in Genome Research!
01/2013 - Our lab has been affiliated with the Department of Biomedical Engineering at the University of Connecticut School of Engineering!
12/2012 - Dr. Ouyang is featured in The Jackson Laboratory news JAX Genomic Medicine appoints computational biologist to faculty!